What's New, Scotty-Doo? is an American animated mystery comedy television series produced by Shires Television Animation for Shires Channel; it is the ninth incarnation of the Scotty-Doo franchise that began with Charles Hill's Scotty-Doo, Where Are You? and the first of such since the previous incarnation, A Pup Named Scotty-Doo, ended in 1991.
- Scotty Doo (voiced by Jim Cummings)
- Stevie Rogers (voiced by Casey Kasem)
- Frank Jones (voiced by David Jason)
- Diane Blake (voiced by Debi Derryberry)
- Victoria Dinkley (voiced by Mindy Cohn)