The Most Popular Girls in School is a live-action film based on a web series.
The adventures of Deandra and her life in high school.
- Elle Fanning as Deandra the New Girl
- Ariel Winter as Mackenzie Zales
- Annalisa Cochrane as Brittnay Matthews
- Katherine McNamara as Trisha Cappelletti
- Mary Mouser as Saison Margeurite
- Chloë Grace Moretz as Shay Van Buren
- Odeya Rush as Ashley Katchadorian
- Sasha Pieterse as Jenna Darabond
- Bella Thorne as Rachel Tice
- Saoirse Ronan as Cameron Van Buren
- Sophie Turner as Bridget Tice
- Mia Talerico as Mikayla Van Buren
- Joe Keery as Tanner Christiansen
- Colin Ford as Tristan McKie
- Louis Hofmann as Jonathan Getslinhaumer
- Ross Lynch as Blaine McClaine
- Jacob Latimore as Matthew Derringer
- It will be distributed by Warner Bros. Pictures.
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