This films stars Eliza Bennett, Ethan Hawke, Max Thieriot, Elizabeth Olsen, Josh Hutcherson, Florence Pugh, Scott Eastwood, Benedict Cumberbatch and Linda Hamilton.
4 years after The Insurrection,
- Eliza Bennett as Serena Harper
- Ethan Hawke as Jake Brackett
- Max Thieriot as Josh Harper
- Elizabeth Olsen as Tamera Olsen
- Josh Hutcherson as Daniel Shaw
- Florence Pugh as Angel Brackett
- Scott Eastwood as Nico Kingsley, a millionaire and the villain of the film. Nico is later revealed as Amanda's son who was taken between the first film and second film.
- TBA as Young Nico Kingsley/Nicholas Brackett (age 14)
- Benedict Cumberbatch as Damien Olsen
- Linda Hamilton as Captain Amanda Coleman, a U.S. Military captain who worked for the colonel and she is Jake's twin sister; she is 14 and a half years older because of Jake being frozen in time and Oliver's sister.
- Heather Graham as Young Amanda Coleman
- Portia Doubleday as Phillipa Coleman, Amanda's daughter, Jake and Oliver's niece and Angel and Ellie's cousin who work for Nico.
- TBA as Young Phillipa Coleman (age 11)
- Pilou Asbæk as Oliver Brackett, Jake and Amanda's younger brother and Nico, Phillipa, Angel, Jacob and Ellie's uncle
- Tye Sheridan as Jacob Coleman, Amanda's son, Nico and Phillipa's brother, Jake and Oliver's nephew and Angel and Ellie's cousin.
- TBA as Young Jacob Coleman (age 5)
- Riley Keough as Sophie Shaw
- Katey Sagal as Molly Shaw
- Chris Vance as Colonel Donald Carver
- Devon Werkheiser as Elliot Harper
- Minka Kelly as Gemma Harper
- Owen Fielding as Kyle Shaw
- TBA as Ellie Brackett
- Henry Cavill as Nicholas Henderson (cameo)
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