Rambo III: First Blood (film) Action-Adventure Thriller upcoming film prequel to Rambo 4: Jungle Blood (film)
- Jordan Quinton Scott as Ale Javíer, foster son of John.￼
- Joseph Swaby as Rambo
- Tyson Tatum as Cole (mentioned only)
- Diego Arcia Sabariego as Kevin Kramer; Jim's oldest son.
- John Henkis Sr. as Phil McDonnie Senior, Phil's father.
- John Henkis Jr. as ￼Philip 'Phil' McDonnie, Jr, Phil's son.
- Lewin Solomon Jr as Jacob Cole
- Eduardo Perez as Carlós Alejandró, an Mexican cartel and main antagonist.
- Emilito Hernandez as Hugo Alejandró, an Mexican cartel and main antagonist.
- Dailet Aguilar as Lily Beltran; Rambo's deceased adoptive niece.
- Yaneils Ramirez Barrio as Diaña Beltran; Rambo's Sister-Figure and Lily's mother.