Family Guy 2.0 is a rebooted version of the original Family Guy show. Like the Simpsons 2.0, Updated with characters voiced by celebrities.
The 2.0 series was cancelled after its final episode.
- Will Smith as Peter Griffin
- Lucy Liu as Lois Griffin
- Sacha Baron Cohen as Chris Griffin
- Danny DeVito as Meg Griffin
- John Oliver as Brian Griffin
- Gary Oldman as Homer Simpson (guest star)
- Angelina Jolie as Marge Simpson (guest star)
- Benedict Cumberbatch as Bart Simpson (guest star)
- Emily Blunt as Lisa Simpson (guest star)
- Oprah Winfrey as Maggie Simpson (guest star)
- Andy Serkis as Moe Szyslak (guest star)
- Jeremy Irons as Mr. Burns (guest star)
- Irons also voices Philip the Unicorn (guest star)
- Dustin Hoffman as Masha (guest star)
- Denis Leary as Diego (guest star)
- Ray Romano as Manny (guest star)
- John de Lancie as Discord (guest star)
- Robert Downey Jr. as Toothless the Night Fury (guest star)
- James Woods as Jimbo Jones (guest star)
- Ian McShane as Kearny (guest star)
- Peter Dinklage as Dolph Starbeam (guest star)
- Will Smith also plays Bozark the Elephant
- Baha Men as themselves (guest stars)
- The characters from Simpsons 2.0 arrived in all of the episodes, due to their show being cancelled and foreshadowing the upcoming movie.
- The episodes have musical numbers.
- The series end with the Peter, Brian, Simpsons, Mr Burns, Moe, Manny, Toothless, Diego, Discord, Bozark, Masha and Phillip going into the portal to the real world, foreshadowing the film.
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